Hydroxypropyl betadextrin has a penetration-promoting effect
Time:
Nov 16,2024
In the transdermal drug delivery preparations of medicine, hydroxypropyl beta cyclodextrin is mainly used, which can increase the absorption of active substances by the skin. Its mechanism of promoting penetration is different from other penetration enhancers. It increases the drug permeability by increasing the concentration of the drug in the supply chamber on the side of the membrane and increasing the concentration of the free drug in the aqueous medium on the surface of the biofilm without changing the tissue structure of the local mucosa, therefore, in cosmetics, we can learn from the preparation of pharmaceutical transdermal preparations of raw materials, the use of hydroxypropyl beta cyclodextrin this feature to increase the skin's absorption of active ingredients in the product, improve the use of products.
and because of the hydroxypropylBeheThe inclusion of cyclodextrin cavity on the active substance, so that the inclusion of the material is stable release, effectively improve the utilization rate of the drug, which has the effect of slow release and controlled release, and the original odor of the material closed and cavity, with obvious deodorization effect, can significantly remove the odor.
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