Application scenarios of water-soluble salicylic acid cyclodextrin inclusion complex
Time:
Apr 01,2025
Water-soluble salicylic acid cyclodextrin inclusion complex isformed by embedding salicylic acid in cyclodextrin.Water-solublesalicylic acid powder. Salicylic acid in medicine can be used to relieve pain and fever, and also has anti-inflammatory effects.Salicylic acidis readily soluble in ethanol, ether, chloroform, benzene, acetoneetc.,insoluble in water (20℃solubilityonlyis0.2g/100ml),andis prone to irritation in cosmetic use. Using hydroxypropylcyclodextrin to include salicylic acid greatly improves the water solubility of salicylic acid, andat the same timeslow release, so it will not cause irritation, is more stable, and has higher utilization rate during use.
The following are some application scenarios of water-soluble salicylic acid cyclodextrin inclusion complexes:
1. Skin care products: Water-soluble salicylic acid cyclodextrin inclusion complexes can be used to prepare various skin care products, such as creams, lotions, and face masks. Water-soluble inclusion complexes can enhance the solubility of salicylic acid in the product, thereby improving the stability and permeability of the product, improving the skin absorption effect, and reducing skin irritation.
2. Oral care products: Water-soluble salicylic acid cyclodextrin inclusion complexes can be used in the formulation of oral care products, such as mouthwash and toothpaste. They can improve the stability and solubility of salicylic acid in oral products, improving the cleaning effect and oral care effect of the product.
3. Anti-inflammatory drugs: Water-soluble salicylic acid cyclodextrin inclusion complexes have anti-inflammatory effects and can be used to prepare various anti-inflammatory drugs. This inclusion complex can improve the stability and solubility of salicylic acid, enhance the therapeutic effect of the drug, and reduce the inflammatory response.
4. Cosmetics: Water-soluble salicylic acid cyclodextrin inclusion complexes can be used in the formulation of various cosmetics, such as shampoos, conditioners, and facial cleansers. They can improve the stability and solubility of salicylic acid in cosmetics, improve the cleaning and care effects of the product, and reduce irritation to the skin and hair.
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