Hydroxypropyl-beta-cyclodextrin molecular inclusion sustained-release technology: Unveiling the magic of intoxicating floral fragrance

Rose essential oil, due to its natural ， low toxicity ， and pure aroma ， In today's increasing pursuit of environmental protection ， and the natural world, it is widely used in various industries. 。 In daily chemicals, it can be used to produce high-end perfumes, 、 shampoos, 、 soaps, 、 potpourri, 、 sachets, 、 bath liquids, and other cosmetic series. ； Rose fragrance is also used in high-grade smoking fragrances, 、 food fragrances, 、 and the blending of wine fragrances. ； In addition, rose fragrance can be used for tea scenting. 。 In recent years, the hottest use of rose fragrance is in aromatherapy. ， Rose essential oil aromatherapy can stimulate nerves and create feelings of love, both mentally and spiritually. 。 Rose essential oil is known as “Queen of Essential Oils” ， Long-term use can not only promote blood circulation, beautify the skin, lower blood lipids, lower cholesterol, promote cell regeneration, delay aging, activate male hormones, improve skin texture, promote blood circulation and metabolism, but also has a body-scenting effect. ， Adding charm to people. In short, ， rose essential oil is increasingly being used in food, cosmetics, tobacco and tea, aromatherapy, and medicine. ， It is loved by many people and has a very broad market prospect.

Hydroxypropyl - β - cyclodextrin special structure gives it many special properties. ， It can interact with a wide range of guest molecules, ， such as organic molecules, 、 inorganic ions, 、 complexes, 、 aromatic compounds, and even inert gases. ， Through intermolecular interactions, host-guest inclusion complexes are formed, ， thus shielding the guest molecules, ， controlling release, ， and protecting activity. 。 Therefore, it is widely used in medicine, daily chemicals, and food. 。 At the same time, utilizing the matching of its cavity size with the guest molecule, ， it can also be used for molecular recognition of various isomers, ， and the preparation of separation materials. 。

   To address the thermal stability and sustained release of rose fragrance, inclusion experiments were conducted using hydroxypropyl-β-cyclodextrin (HP-β-CD). Utilizing its unique cavity structure, rose fragrance was successfully encapsulated at the nanoscale. Experiments showed that the thermal stability of nano rose fragrance was significantly improved, and its heat resistance was significantly better than that of ordinary fragrance. Furthermore, due to the hydrophobic cavity structure of HP-β-CD, the sustained-release performance of nano rose fragrance was also significantly improved. This technology, using a water solution complexation method, not only improves the quality of rose fragrance but also provides new ideas and methods for the preparation of nano fragrance. This discovery is expected to revolutionize the fragrance industry, providing higher quality and more stable fragrance products for the food and cosmetics industries.