Central Ring Zhongjie's New Product Launch — Water-Soluble Salicylic Acid

Salicylic acid is a widely used active ingredient. , in cosmetics Its main uses include removing acne, balancing oil and moisture, whitening, and treating superficial fungal skin infections, among others. By High concentrations of salicylic acid may cause some skin irritation, since 1999 Starting this year, China's health authorities have stipulated that the concentration of salicylic acid in cosmetics must be limited to 0.2% To 1.5% Between them, and the relevant products must bear warning labels to ensure safety during long-term use.

How to efficiently and conveniently use salicylic acid has become a critical issue in the cosmetics industry. To make the most of salicylic acid, the key lies in addressing its poor water solubility and strong irritancy. Faced with these two major challenges, a solution that seamlessly combines both advantages—enabling a "two birds with one stone" approach—has emerged: incorporating salicylic acid into cyclodextrin derivatives to prepare… Water-soluble salicylic acid . After inclusion, it can both enhance the water solubility of salicylic acid and It can effectively regulate its release behavior on the skin surface, controlling local drug concentrations while significantly reducing its irritancy and potential toxic side effects on the skin—thus avoiding adverse reactions caused by excessively high concentrations.   

Shandong Zhonghuan Zhongjie Bio-Technology Co., Ltd. focuses on market demand and, through independent research and development, has created multiple models of water-soluble salicylic acid products to meet consumer needs.

Product Model: 10% Salicylic acid cyclodextrin inclusion complex, 40% Water-soluble salicylic acid and 50% Water-soluble salicylic acid , for customers to choose from.

The primary innovation principle behind these products is achieved through To Monomer Structural modification of cyclodextrins can yield hydrophilic derivatives. (Such as hydroxypropyl cyclodextrin, methylcyclodextrin, and others), this type Cyclodextrins have a hydrophobic interior cavity and a hydrophilic outer rim, allowing them to encapsulate drug molecules of appropriate size. (Such as salicylic acid molecules) Forming host-guest inclusion complexes. Such inclusion complexes can significantly enhance drug solubility, modulate release rates, improve stability, optimize formulation performance, and reduce the irritancy and toxic side effects of the drug. Salicylic acid-cyclodextrin inclusion complexes demonstrate excellent safety, biocompatibility, as well as stability during production and storage.