2,6-Di-O-methyl-Beta-cyclodextrin

2.6-Di-O-methyl-Beta-cyclodextrin CAS 51166-71-3

Product Introduction

2.6-di-O-methyl-beta-CyclodextrinWith strong water and oil-solubility, as the stromal molecule to include the complexes and to be used in including of drugs spices etc.It can change the original natures of materials ,in medical field ,it can promote the dissolusion efficiency of the drugs, enhancing bioavailability and solubility of drugs, so that to reduce the dose but increase the efficacy. it can adjust and controls the releasing of drugs, to enhance the stability. It can changes mmucosa sbsorption in drugs, specially for the oil soluble molecules it can be more effective to increase the water solubility.

Basic information

Product Name : 2.6-di-O-methyl-beta-Cyclodextrin

CAS NO. : 51166-71-3

Synonyms : 2.6-di-O-methyl-β-Cyclodextrin

Abbreviation ：DMBCD

Molecular Formula : C56H98O35

Molecular Weight : 1331.36

Standard : enterprise standard

Usage of 2.6-di-o-methyl-beta-cyclodextrin

Can increase the solubility of the medicine and biological availability.

Can add up the good effect and decrease the dose.

Can control or adjust the reactive speed, lower the drug toxicity and enhance the stability of drugs.

Especially 2.6-dimethyl-beta-cyclodextrin is more effective for the oil-soluble molecules of water-soluble.

Characteristics of Methyl Beta Cyclodextrin and Its Application in Coating Thickener

Methyl beta cyclodextrin (M-β-CD) is the most effective cosolvent for insoluble substances and the best stabilizer for many chemicals. Because M-β-CD has excellent solubilization and inclusion, and because it is soluble in water and organic solvents, it is widely used in medicine, food, pesticide, cosmetics, daily chemicals, chemical industry, textile dyeing and finishing, chromatographic analysis and functional materials.

Beyond pharmaceuticals, 2,6-DM-β-CD finds applications in biotechnology and industrial processes. It is used as a stabilizing agent for proteins and enzymes, preventing aggregation and denaturation while maintaining biological activity. In the food and cosmetics industries, it serves as a carrier for flavors, fragrances, and active ingredients, improving their stability and controlled release. Furthermore, its ability to solubilize hydrophobic compounds makes it useful in environmental remediation, where it can enhance the extraction of organic pollutants from soil and water.  

Despite its advantages, the use of 2,6-DM-β-CD requires careful consideration of potential toxicity and regulatory constraints. While generally regarded as safe, modified cyclodextrins must undergo rigorous testing to ensure biocompatibility, particularly in injectable drug formulations. Researchers continue to explore structural optimizations and novel derivatives to further improve the performance and safety profile of 2,6-DM-β-CD.  

In conclusion, 2,6-Di-O-methyl-β-cyclodextrin represents a versatile and valuable tool in modern science and industry. Its enhanced solubility, molecular encapsulation properties, and selective binding capabilities make it indispensable in drug delivery, analytical chemistry, and biotechnology. As research progresses, new applications and derivatives of this modified cyclodextrin are likely to emerge, further expanding its role in advancing pharmaceutical and industrial innovations.