Beta Cyclodextrin CAS 7585-39-9
Subcategory:
Natural Cyclodextrins
Feature of Beta Cyclodextrin
β-Cyclodextrin is a cyclic heptamer composed of seven glucose units joined "head-to-tail" by alpha-1.4 links. It is produced by the action of the enzyme, cyclodextrin glycosyl transferase (CGT)，on hydrolyzed starch syrups. And it is white powder and there is a cavity in its molecule which can form inclusion compounds with a range of molecules. The solubility degree of Beta-cyclodextrin in water is 1.85 g/100ml @ 25°C, melting point is about 260℃, internal diameter is 0.7-0.8nm.
Basic information of Beta Cyclodextrin
Product Name: Beta Cyclodextrin
CAS NO.: 7585-39-9
Synonyms：β-cyclodextrin ; Cyclomaltoheptaose;beta-Cycloamylose; beta-Cycloheptaamylose; beta-Dextrin
Abbreviation : BCD
Molecular Formula : C42H70O35
Molecular Weight: 1134.98
Grade : Pharmaceutical grade
Application:
Beta cyclodextrin is widely used in the separation of organic compounds and for organic synthesis, as well as medical excipients and food additives. The inclusion of natural cyclodextrin and modified cyclodextrin and some drug molecules that are not biocompatible are now prepared. It not only increases the biocompatibility of the drug, but also plays the role of sustained release.
| TEMS | SPECIFICATION | |
| Appearance | White, practically odorless, fine crystalline powder having a slightly sweet taste. Sparingly soluble in water | |
| Identification | IR | same absorption bands as USP Beta Cyclodextrin RS |
| LC | the retention time of the major peak of sample solution corresponds to the standard solution | |
| Optical rotation | +160°～+164° | |
| Iodine test solution | A yellow-brown precipitate is formed | |
| Residue on Ignition | ≤ 0.1% | |
| Reducing Sugars | ≤ 0.2% | |
| Light-absorbing impurities | Between 230 nm and 350 nm,the absorbance is not greater than 0.10; and between 350 nm and 750 nm, the absorbance is not greater than 0.05 | |
| Alpha cyclodextrin | ≤0.25％ | |
| Gamma cyclodextrin | ≤0.25％ | |
| Other related substances | ≤0.5％ | |
| Water determination | ≤14.0％ | |
| Color and Clarity of Solution | A 10mg/ml solution is clear and Colorless | |
| pH | 5.0~8.0 | |
| Assay | 98.0%°～102.0% | |
| The total aerobic microbial count | ≤1000cfu/g | |
| The total combined moulds and yeasts count | ≤100cfu/g | |
Natural Cyclodextrins
keyword:
Beta Cyclodextrin CAS 7585-39-9